HMGB1 MEDIATES INVASION AND PD-L1 EXPRESSION THROUGH RAGE-PI3K/AKT SIGNALING PATHWAY IN MDA-MB-231 BREAST CANCER CELLS

HMGB1 mediates invasion and PD-L1 expression through RAGE-PI3K/AKT signaling pathway in MDA-MB-231 breast cancer cells

Abstract Background High-mobility group box 1 (HMGB1) is increased in breast cancer cells as the result of exposure to the secreted substances from cancer-associated fibroblasts and plays a crucial role in cancer progression and drug resistance.Its effect, however, on the expression of programmed death ligand 1 (PD-L1) in breast cancer cells has no

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